BDBM31044 1-Ethyl-6-methyl-3-thiophen-2-yl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1-ethyl-6-methyl-3-(2-thienyl)pyrimido[5,4-e][1,2,4]triazine-5,7-quinone::1-ethyl-6-methyl-3-thiophen-2-yl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1-ethyl-6-methyl-3-thiophen-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::MLS000033110::SMR000008918::US9073941, 610::cid_653297
SMILES CCn1nc(nc2c1nc(=O)n(C)c2=O)-c1cccs1
InChI Key InChIKey=DMDNERFCUCYCGM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 31044
Affinity DataKd: 365nMAssay Description:AlphaScreen technology based high-throughput (ALPHA) assay is used to identify inhibitors of Hsp90-TPR2A interaction.More data for this Ligand-Target Pair
Affinity DataKd: 308nMpH: 8.0Assay Description:A fluorescence polarization (FP) assay monitor the fluorescein-labeled C-terminal Hsp90 peptide-TPRA interaction. FP assay will also confirm binding...More data for this Ligand-Target Pair
Affinity DataEC50: 1.21E+3nMT: 2°CAssay Description:Cell assay using BT474, SKBR3 and MCF-12F cell lines measured by WST-1 colorimetric cell proliferation assay.More data for this Ligand-Target Pair